All functions |
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Cibersort reference |
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Adjust transcript abundance for unwanted variation |
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Aggregates multiple counts from the same samples (e.g., from isoforms), concatenates other character columns, and averages other numeric columns |
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as_SummarizedExperiment |
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Get matrix from tibble |
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Get clusters of elements (e.g., samples or transcripts) |
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Get cell type proportions from samples |
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Get DESCRIPTION from gene SYMBOL for Human and Mouse |
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Fill transcript abundance if missing from sample-transcript pairs |
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Produces the bibliography list of your workflow |
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Identify abundant transcripts/genes |
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impute transcript abundance if missing from sample-transcript pairs |
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keep_abundant |
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keep_abundant |
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Filter to keep only abundant transcripts/genes |
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Keep variable transcripts |
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log10_reverse_trans |
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logit scale |
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Extract sample-wise information |
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Extract transcript-wise information |
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Normalise by quantiles the counts of transcripts/genes |
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Dimension reduction of the transcript abundance data |
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Drop redundant elements (e.g., samples) for which feature (e.g., transcript/gene) abundances are correlated |
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resolve_complete_confounders_of_non_interest |
Resolve Complete Confounders of Non-Interest |
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Rotate two dimensions (e.g., principal components) of an arbitrary angle |
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Scale the counts of transcripts/genes |
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Perform differential transcription testing using edgeR quasi-likelihood (QLT), edgeR likelihood-ratio (LR), limma-voom, limma-voom-with-quality-weights or DESeq2 |
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Perform differential expression testing using edgeR quasi-likelihood (QLT), edgeR likelihood-ratio (LR), limma-voom, limma-voom-with-quality-weights or DESeq2 |
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analyse gene enrichment with EGSEA |
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analyse gene over-representation with GSEA |
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analyse gene rank with GSEA |
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test_stratification_cellularity |
Needed for tests tximeta_summarizeToGene_object, It is SummarizedExperiment from tximeta |
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Needed for vignette vignette_manuscript_signature_boxplot |
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Needed for vignette vignette_manuscript_signature_tsne |
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Needed for vignette vignette_manuscript_signature_tsne2 |